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61 – 120 of 152 cards where the cards aren’t reprints and the card is tagged “sweeper-creature-destroy”

Depopulate (Streets of New Capenna #10)
Amalia Benavides Aguirre (The Lost Caverns of Ixalan #221)
Life's Finale (New Phyrexia #65)
Welcome to . . . // Jurassic Park (Jurassic World Collection #7)
Welcome to . . . // Jurassic Park (Jurassic World Collection #7)
Shatter the Sky (Theros Beyond Death #37)
Obliterate (Invasion #156)
Sivitri, Dragon Master (Dominaria United Commander #43)
Planar Outburst (Battle for Zendikar #42)
Tegwyll's Scouring (Wilds of Eldraine Commander #16)
Jokulhaups (Ice Age #195)
Iridian Maelstrom (Dominaria United Commander #12)
Reiver Demon (Mirrodin #75)
Cacophony Unleashed (Commander Masters #730)
Selfless Glyphweaver // Deadly Vanity (Strixhaven: School of Mages #157)
Selfless Glyphweaver // Deadly Vanity (Strixhaven: School of Mages #157)
Harsh Mercy (Onslaught #39)
The Tabernacle at Pendrell Vale (Legends #307)
Unstable Glyphbridge // Sandswirl Wanderglyph (The Lost Caverns of Ixalan #41)
Unstable Glyphbridge // Sandswirl Wanderglyph (The Lost Caverns of Ixalan #41)
Kirtar's Wrath (Odyssey #28)
Don't Move (Jurassic World Collection #1)
End Hostilities (Khans of Tarkir #8)
Valiant Endeavor (Forgotten Realms Commander #13)
Mogg Infestation (Stronghold #93)
Catastrophe (Urza's Saga #6)
Dread Cacodemon (Commander 2011 #79)
Bontu's Last Reckoning (Hour of Devastation #60)
Final Showdown (Outlaws of Thunder Junction #11)
Retribution of the Meek (Visions #19)
Magus of the Disk (Time Spiral #27)
Sublime Exhalation (Commander 2016 #5)
Necroplasm (Ravnica: City of Guilds #98)
The Night of the Doctor (Doctor Who #24)
Nevinyrral, Urborg Tyrant (Commander Legends #287)
Puppet's Verdict (Mercadian Masques #208)
Fight to the Death (Alara Reborn #97)
Angrath, Minotaur Pirate (Rivals of Ixalan #201)
Whirlwind (Urza's Saga #283)
Celestial Judgment (Midnight Hunt Commander #5)
Myojin of Cleansing Fire (Champions of Kamigawa #35)
Fated Retribution (Born of the Gods #11)
Path of Peril (Innistrad: Crimson Vow #124)
Do or Die (Invasion #102)
Ritual of Soot (Guilds of Ravnica #84)
Planar Collapse (Urza's Legacy #18)
Spreading Plague (Invasion #125)
March of Souls (Planeshift #10)
Devastation (Portal #123)
Novablast Wurm (Worldwake #119)
Overwhelming Forces (Portal Three Kingdoms #79)
Solar Tide (Mirrodin #24)
Consume the Meek (Rise of the Eldrazi #100)
Grim Giganotosaurus (Jurassic World Collection #11)
Hythonia the Cruel (Theros #91)
Breaking Point (Judgment #81)
The Nipton Lottery (Fallout #113)
No Witnesses (Murders at Karlov Manor #27)
Death-Rattle Oni (March of the Machine: The Aftermath #13)
Mageta the Lion (Prophecy #13)
Deadly Cover-Up (Murders at Karlov Manor #83)
Total War (Ice Age #221)
Desolation Giant (Apocalypse #59)
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