25 cards where the cards aren’t reprints and the mana cost is greater than or equal to {2}{G}{U}{R}

Miirym, Sentinel Wyrm (Commander Legends: Battle for Baldur's Gate #284)
Maelstrom Wanderer (Planechase 2012 #101)
Surrak Dragonclaw (Khans of Tarkir #206)
The Ur-Dragon (Commander 2017 #48)
Tiamat (Adventures in the Forgotten Realms #235)
Sarkhan Unbroken (Dragons of Tarkir #230)
Xyris, the Writhing Storm (Commander 2020 #18)
Conflux (Conflux #102)
Unite the Coalition (Dominaria United Commander #15)
Intet, the Dreamer (Planar Chaos #158)
Illuna, Apex of Wishes (Ikoria: Lair of Behemoths #190)
Primeval Spawn (Dominaria United Commander #13)
The First Tyrannic War (Warhammer 40,000 Commander #121)
Riku of Two Reflections (Commander 2011 #220)
The Swarmlord (Warhammer 40,000 Commander #4)
Gimbal, Gremlin Prodigy (March of the Machine Commander #3)
Beluna Grandsquall // Seek Thrills (Wilds of Eldraine #220)
Borborygmos and Fblthp (March of the Machine #219)
Me, the Immortal (Doctor Who #147)
Meeting of the Five (Streets of New Capenna #202)
Avalanche Tusker (Khans of Tarkir #166)
Bear's Companion (Khans of Tarkir #167)
Snowhorn Rider (Khans of Tarkir #201)
Coalition Victory (Invasion #241)
Who // What // When // Where // Why (Unhinged #120)

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